hrp0089p2-p149 | Fat, Metabolism and Obesity P2 | ESPE2018

Galanin is Positively Correlated with Insulin Resistance and Triglyceride Levels in Obese Children

Acar Sezer , Paketci Ahu , Kume Tuncay , Demir Korcan , Calan Ozlem Gursoy , Bober Ece , Abacı Ayhan

Introduction: Galanin is a neuropeptide involved in the regulation of food intake and glucose homeostasis. The objective of this study was to assess the relation of serum galanin levels with anthropometric and metabolic parameters in obese and healthy children.Material and methods: This cross-sectional study consisted of 38 obese children (mean age, 11.9±3.0 years) and 30 healthy children (mean age, 11.4±2.0 years). Clinical and biochemical [gl...

hrp0082p3-d1-765 | Fat Metabolism & Obesity | ESPE2014

The Relation of Serum Leptin and Soluble Leptin Receptor Levels with Metabolic and Clinical Parameters in Obese and Healthy Children

Catli Gonul , Anik Ahmet , Tuhan Hale Unver , Kume Tuncay , Bober Ece , Abaci Ayhan

Background: In blood, leptin is suggested to circulate both in the free form as well as bound to soluble leptin receptor (sLR) and possibly also to other as yet unidentified binding protein. However, the role of the sLR in the regulation of the physiological function of leptin is until now unclear.Objective and hypotheses: We aimed to investigate the relation of serum leptin and sLR levels with metabolic and anthropometric parameters in obese and healthy...

hrp0084p2-358 | Fat | ESPE2015

Elevated Serum Irisin Level is not Related to Metabolic and Anthropometric Parameters in Obese Children

Abaci Ayhan , Catli Gonul , Tuhan Hale Unver , Anik Ahmet , Kume Tuncay , Calan Ozlem Gursoy , Bober Ece

Background: Irisin is a newly discovered myokine which regulates energy metabolism and obesity (type 2 diabetes pathogenesis). However, results of the clinical studies investigating the relation of irisin with metabolic and anthropometric parameters remain controversial, and studies in obese children are limited.Objective and hypotheses: We aimed to investigate the relation of serum irisin level with metabolic and anthropometric parameters in obese child...

hrp0094p2-4 | Adrenals and HPA Axis | ESPE2021

Serum Sex Hormone Binding Globulin Levels, But Not 4-Hour Profile of 17-Oh Progesterone, Would Be Useful in Monitoring Children with Congenital Adrenal Hyperplasia

Besci Ozge , Erbas Ibrahim Mert , Kume Tuncay , Acinikli Kubra Yuksek , Abacı Ayhan , Bober Ece , Demir Korcan ,

Background: There exists no gold standard for adjustment of treatment in congenital adrenal hyperplasia. Clinicians try to avoid over-and undertreatment by considering various indicators. We aimed to investigate the sampling times of 17-hydroxyprogesterone (17-OHP) and the use of sex hormone-binding globulin (SHBG) as a monitoring parameter, the association of which was not studied with clinical features. Materials and Methods: This cross-sectional study inclu...